DJ-1 and α-synuclein in human cerebrospinal fluid as biomarkers of Parkinson’s disease

Hong, Zhen; Shi, Min; A. Chung, Kathryn; F. Quinn, Joseph; R. Peskind, Elaine; Galasko, Douglas; Jankovic, Joseph; P. Zabetian, Cyrus; B. Leverenz, James; S. Baird, Geoffrey; J. Montine, Thomas; M. Hancock, Aneeka; Hwang, Hye‐Jin; Pan, Catherine; M. Bradner, Joshua; Jung Kang, Un; Henning Jensen, Poul; Zhang, Jing

doi:10.1093/brain/awq008

Public

DJ-1 and α-synuclein in human cerebrospinal fluid as biomarkers of Parkinson’s disease

Published in Brain • Feb 15, 2010

Authors:

Zhen Hong

Min Shi

Kathryn A. Chung

Abstract

Biomarkers are urgently needed for the diagnosis and monitoring of disease progression in Parkinson's disease. Both DJ-1 and alpha-synuclein, two proteins critically involved in Parkinson's disease pathogenesis, have been tested as disease biomarkers in several recent studies with inconsistent resul...

Subject

Cerebrospinal fluid

Parkinson's disease

Medicine

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