Functional Expression of Brain Neuronal CB2 Cannabinoid Receptors Are Involved in the Effects of Drugs of Abuse and in Depression

S. Onaivi, Emmanuel; Ishiguro, Hiroki; Gong, Jianping; Sejal, Patel; A. Meozzi, Paul; H. Myers, Lester; Perchuk, Alex; Mora, Zoila; Tagliaferro, Patricia; Gardner, Eileen; Brusco, Alicia; Emmanuel Akinshola, B.; Liu, Qing‐Rong; Chirwa, Sanika; T. Hope, Bruce; Lujilde, Javier; Inada, Toshiya; Iwasaki, Shinya; Macharia, David; Teasenfitz, Lindsey; Arinami, Tadao; R. Uhl, George

doi:10.1196/annals.1432.036

Public

Functional Expression of Brain Neuronal CB2 Cannabinoid Receptors Are Involved in the Effects of Drugs of Abuse and in Depression

Published in Annals of the New York Academy of Sciences • Oct 1, 2008

Authors:

Emmanuel S. Onaivi

Hiroki Ishiguro

Jianping Gong

Abstract

Major depression and addiction are mental health problems associated with stressful events in life with high relapse and recurrence even after treatment. Many laboratories were not able to detect the presence of CB2 cannabinoid receptors (CB2-Rs) in healthy brains, but CB2-R expression has been demo...

Subject

Cannabinoid receptor type 2

Endocannabinoid system

Cannabinoid receptor

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