Impact of additional cytogenetic aberrations at diagnosis on prognosis of CML: long-term observation of 1151 patients from the randomized CML Study IV

Fabarius, Alice; Leitner, Armin; Hochhaus, Andreas; C. Müller, Martin; Hanfstein, Benjamin; Haferlach, Claudia; Göhring, Gudrun; Schlegelberger, Brigitte; Jotterand, Martine; Reiter, Andreas; Jung-Munkwitz, Susanne; Proetel, Ulrike; Schwaab, Juliana; Hofmann, Wolf‐Karsten; Schubert, Jörg; Einsele, Hermann; D. Ho, Anthony; Falge, Christiane; Kanz, Lothar; Neubauer, Andreas; Kneba, Michael; Stegelmann, Frank; Pfreundschuh, Michael; F. Waller, Cornelius; Spiekermann, Karsten; M. Baerlocher, Gabriela; Lauseker, Michael; Pfirrmann, Markus; Hasford, Joerg; Saußele, Susanne; Hehlmann, Rüdiger; the Schweizerische Arbeitsgemeinschaft für Klinische Krebsforschung (SAKK) and the German CML Study Group, for

doi:10.1182/blood-2011-08-373902

Public

Impact of additional cytogenetic aberrations at diagnosis on prognosis of CML: long-term observation of 1151 patients from the randomized CML Study IV

Published in Blood • Oct 29, 2011

Authors:

Alice Fabarius

Armin Leitner

Andreas Hochhaus

Abstract

The prognostic relevance of additional cytogenetic findings at diagnosis of chronic myeloid leukemia (CML) is unclear. The impact of additional cytogenetic findings at diagnosis on time to complete cytogenetic (CCR) and major molecular remission (MMR) and progression-free (PFS) and overall survival ...

Subject

Isochromosome

Internal medicine

Medicine

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