Celecoxib versus Diclofenac and Omeprazole in Reducing the Risk of Recurrent Ulcer Bleeding in Patients with Arthritis

K.L. Chan, Francis; C.T. Hung, Lawrence; Yee Suen, Bing; C. Wu, Justin; C. Lee, Kenneth; K S Leung, Vincent; J. Hui, Aric; To, Ka‐Fai; K. Leung, Wai; Wai‐Sun Wong, Vincent; Sydney Chung, S.C.; J.�Y. Sung, Joseph

doi:10.1056/nejmoa021907

Public

Celecoxib versus Diclofenac and Omeprazole in Reducing the Risk of Recurrent Ulcer Bleeding in Patients with Arthritis

Published in New England Journal of Medicine • Dec 25, 2002

Authors:

Francis K.L. Chan

Lawrence C.T. Hung

Bing Yee Suen

Abstract

BACKGROUND: Current guidelines recommend that patients at risk for ulcer disease who require treatment for arthritis receive nonsteroidal antiinflammatory drugs (NSAIDs) that are selective for cyclooxygenase-2 or the combination of a nonselective NSAID with a proton-pump inhibitor. We assessed wheth...

Subject

Medicine

Diclofenac

Celecoxib

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