Effects of Hydroxychloroquine on Symptomatic Improvement in Primary Sjögren Syndrome

Gottenberg, Jacques‐Eric; Ravaud, Philippe; Puéchal, Xavier; Le Guern, Véronique; Sibilia, Jean; Goëb, Vincent; Larroche, C.; Dubost, Jean‐Jacques; Rist, S.; Saraux, Alain; Devauchelle‐Pensec, Valérie; Morel, Jacques; Hayem, Gilles; Hatron, P.Y.; Perdriger, Aleth; Sène, D.; Zarnitsky, Charles; Batouche, Djilali; Furlan, Valérie; Bénessiano, Joëlle; Perrodeau, Élodie; Séror, Raphaèle; Mariette, Xavier

doi:10.1001/jama.2014.7682

Public

Effects of Hydroxychloroquine on Symptomatic Improvement in Primary Sjögren Syndrome

Published in JAMA • Jul 15, 2014

Authors:

Jacques‐Eric Gottenberg

Philippe Ravaud

Xavier Puéchal

Abstract

IMPORTANCE: Primary Sjögren syndrome is a systemic autoimmune disease characterized by mouth and eye dryness, pain, and fatigue. Hydroxychloroquine is the most frequently prescribed immunosuppressant for the syndrome. However, evidence regarding its efficacy is limited. OBJECTIVE: To evaluate the ef...

Subject

Hydroxychloroquine

Medicine

Placebo

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