Endocytosis of Chikungunya Virus into Mammalian Cells: Role of Clathrin and Early Endosomal Compartments

Bernard, Éric; Solignat, Maxime; Gay, Bernard; Chazal, Nathalie; Higgs, Stephen; Devaux, Christian; Briant, Laurence

doi:10.1371/journal.pone.0011479

Public

Endocytosis of Chikungunya Virus into Mammalian Cells: Role of Clathrin and Early Endosomal Compartments

Published in PLoS ONE • Jul 8, 2010

Authors:

Éric Bernard

Maxime Solignat

Bernard Gay

Abstract

BACKGROUND: The replicative cycle of chikungunya virus (CHIKV), an alphavirus that recently re-emerged in India and in Indian Ocean area, remains mostly unknown. The aim of the present study was to investigate the intracellular trafficking pathway(s) hijacked by CHIKV to enter mammalian cells. METHO...

Subject

Endocytosis

Clathrin

Endosome

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