Inhibition of Autophagy Contributes to Ischemic Postconditioning-Induced Neuroprotection against Focal Cerebral Ischemia in Rats

Gao, Li; Jiang, Teng; Guo, Jun; Liu, Yi; Cui, Guiyun; Gu, Li-Ze; Su, Ling-ying; Zhang, Yingdong

doi:10.1371/journal.pone.0046092

Public

Inhibition of Autophagy Contributes to Ischemic Postconditioning-Induced Neuroprotection against Focal Cerebral Ischemia in Rats

Published in PLoS ONE • Sep 28, 2012

Authors:

Li Gao

Teng Jiang

Jun Guo

Abstract

BACKGROUND: Ischemic postconditioning (IPOC), or relief of ischemia in a stuttered manner, has emerged as an innovative treatment strategy to reduce programmed cell death, attenuate ischemic injuries, and improve neurological outcomes. However, the mechanisms involved have not been completely elucid...

Subject

Autophagy

Neuroprotection

Ischemia

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