Role of the Major Antigen of
            <i>Mycobacterium tuberculosis</i>
            in Cell Wall Biogenesis

T. Belisle, John; D. Vissa, Varalakshmi; Sievert, Todd; Takayama, Kuni; J. Brennan, Patrick; S. Besra, Gurdyal

doi:10.1126/science.276.5317.1420

Public

Role of the Major Antigen of Mycobacterium tuberculosis in Cell Wall Biogenesis

Shared by NobleBlocks on May 28, 1997 • 12:00 AM UTC

Authors:

John T. Belisle

Varalakshmi D. Vissa

Todd Sievert

Abstract

The dominant exported proteins and protective antigens of Mycobacterium tuberculosis are a triad of related gene products called the antigen 85 (Ag85) complex. Each has also been implicated in disease pathogenesis through its fibronectin-binding capacities. A carboxylesterase domain was found within...

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