Multiple homologues of LuxR and LuxI control expression of virulence determinants and secondary metabolites through quorum sensing in Pseudomonas aeruginosa PAO1

Latifi, Amel; K. Winson, Michael; Foglino, Maryline; W. Bycroft, Barrie; S.A.B. Stewart, Gordon; Lazdunski, Andrée; Williams, Paul

doi:10.1111/j.1365-2958.1995.mmi_17020333.x

Public

Multiple homologues of LuxR and LuxI control expression of virulence determinants and secondary metabolites through quorum sensing in Pseudomonas aeruginosa PAO1

Published in Molecular Microbiology • Jul 1, 1995

Authors:

Amel Latifi

Michael K. Winson

Maryline Foglino

Abstract

In Pseudomonas aeruginosa PAO1, expression of elastase is dependent upon an interaction between the positive transcriptional activator LasR and the auto-inducer molecule N-(3-oxododecanoyl)-L-homoserine lactone (OdDHL), the synthesis of which is directed by LasI. Previously we have shown that in PAN...

Subject

Quorum sensing

Autoinducer

Pyocyanin

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!