Resistance to Linezolid Is Mediated by the<i>cfr</i>Gene in the First Report of an Outbreak of Linezolid‐Resistant<i>Staphylococcus aureus</i>

Morales, Gracia; J. Picazo, Juan; Baos, Elvira; Javier Candel, Francisco; Arribi, A; Armada Peláez, B.; Sales de Andrade, Raquel; de la Torre, M.; Fereres, J.; Sánchez García, Miguel

doi:10.1086/650574

Public

Resistance to Linezolid Is Mediated by thecfrGene in the First Report of an Outbreak of Linezolid‐ResistantStaphylococcus aureus

Published in Clinical Infectious Diseases • Feb 9, 2010

Authors:

Gracia Morales

Juan J. Picazo

Elvira Baos

Abstract

BACKGROUND: From April through June 2008, we identified 12 patients in the intensive care unit and 3 patients on other wards infected with methicillin-resistant Staphylococcus aureus that was also resistant to linezolid. We investigated the mechanism of resistance--point mutations in domain V of 23S...

Subject

23S ribosomal RNA

Linezolid

Microbiology

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