Duodenal and Gastric Ulcer Prevention with Misoprostol in Arthritis Patients Taking NSAIDs

Y. Graham, David; H. White, Richard; W. Moreland, Larry; T. Schubert, Timothy; Katz, Robert; Jaszewski, Richard; Tindall, Elizabeth; Triadafilopoulos, George; C. Stromatt, Scott; S. Teoh, Leah; Misoprostol Study Group., and

doi:10.7326/0003-4819-119-4-199308150-00001

Public

Duodenal and Gastric Ulcer Prevention with Misoprostol in Arthritis Patients Taking NSAIDs

Published in Annals of Internal Medicine • Aug 15, 1993

Authors:

David Y. Graham

Richard H. White

Larry W. Moreland

Abstract

OBJECTIVES: To determine the efficacy of misoprostol for the prevention of nonsteroidal anti-inflammatory drug (NSAID)-induced duodenal and gastric ulcers in arthritis patients receiving NSAID therapy. DESIGN: A randomized, double-blind, multicenter, placebo-controlled trial. SETTING: Six hundred th...

Subject

Medicine

Misoprostol

Placebo

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