Incomplete meiotic sex chromosome inactivation in the domestic dog

Federici, Federica; Mulugeta, Eskeatnaf; Schoenmakers, Sam; Wassenaar, Evelyne; W. Hoogerbrugge, Jos; W. van der Heijden, Godfried; A. van Cappellen, Wiggert; A. Slotman, Johan; F. J. van IJcken, Wilfred; S.E. Laven, Joop; Anton Grootegoed, J.; M. Baarends, Willy

doi:10.1186/s12864-015-1501-9

Public

Incomplete meiotic sex chromosome inactivation in the domestic dog

Published in BMC Genomics • Apr 11, 2015

Authors:

Federica Federici

Eskeatnaf Mulugeta

Sam Schoenmakers

Abstract

BACKGROUND: In mammalian meiotic prophase, homologous chromosome recognition is aided by formation and repair of programmed DNA double-strand breaks (DSBs). Subsequently, stable associations form through homologous chromosome synapsis. In male mouse meiosis, the largely heterologous X and Y chromoso...

Subject

Synapsis

Biology

Pseudoautosomal region

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