A Comparison of Four Treatments for Generalized Convulsive Status Epilepticus

M. Treiman, David; D. Meyers, Patti; Y. Walton, Nancy; F. Collins, Joseph; Colling, Cindy; James Rowan, A.; Handforth, Adrian; Faught, Edward; P. Calabrese, Vincent; M. Uthman, Basim; Eugene Ramsay, R.; B. Mamdani, Meenal; M. Yagnik, Pratap; Jones, J.C.; Barry, Elizabeth; Boggs, Jane; M. Kanner, Andrés

doi:10.1056/nejm199809173391202

Public

A Comparison of Four Treatments for Generalized Convulsive Status Epilepticus

Published in New England Journal of Medicine • Sep 17, 1998

Authors:

David M. Treiman

Patti D. Meyers

Nancy Y. Walton

Abstract

BACKGROUND AND METHODS: Although generalized convulsive status epilepticus is a life-threatening emergency, the best initial drug treatment is uncertain. We conducted a five-year randomized, double-blind, multicenter trial of four intravenous regimens: diazepam (0.15 mg per kilogram of body weight) ...

Subject

Phenytoin

Status epilepticus

Lorazepam

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