Rivaroxaban versus Enoxaparin for Thromboprophylaxis after Total Knee Arthroplasty

R. Lassen, Michael; Ageno, Walter; C. Borris, Lars; R. Lieberman, Jay; Rosencher, Nadia; J. Bandel, Tiemo; Misselwitz, Frank; G.G. Turpie, Alexander

doi:10.1056/nejmoa076016

Public

Rivaroxaban versus Enoxaparin for Thromboprophylaxis after Total Knee Arthroplasty

Published in New England Journal of Medicine • Jun 25, 2008

Authors:

Michael R. Lassen

Walter Ageno

Lars C. Borris

Abstract

BACKGROUND: We investigated the efficacy of rivaroxaban, an orally active direct factor Xa inhibitor, in preventing venous thrombosis after total knee arthroplasty. METHODS: In this randomized, double-blind trial, 2531 patients who were to undergo total knee arthroplasty received either oral rivarox...

Subject

Medicine

Rivaroxaban

Arthroplasty

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