Adjuvant Radiotherapy and Chemotherapy in Node-Positive Premenopausal Women with Breast Cancer

Ragaz, Joseph; M. Jackson, Stewart; Le, Nhu; H. Plenderleith, Ian; J. Spinelli, John; E. Basco, Vivian; S. Wilson, Kenneth; A. Knowling, Margaret; Coppin, C; Paradis, Marilyn; J. Coldman, Andrew; A. Olivotto, Ivo

doi:10.1056/nejm199710023371402

Public

Adjuvant Radiotherapy and Chemotherapy in Node-Positive Premenopausal Women with Breast Cancer

Published in New England Journal of Medicine • Oct 2, 1997

Authors:

Joseph Ragaz

Stewart M. Jackson

Nhu Le

Abstract

BACKGROUND: Radiotherapy after mastectomy to treat early breast cancer has been known since the 1940s to reduce rates of local relapse. However, the routine use of postoperative radiotherapy began to decline in the 1980s because it failed to improve overall survival. We prospectively tested the effi...

Subject

Medicine

Radiation therapy

Breast cancer

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