Pulmonary Oxidative Stress, Inflammation and Cancer: Respirable Particulate Matter, Fibrous Dusts and Ozone as Major Causes of Lung Carcinogenesis through Reactive Oxygen Species Mechanisms

Valavanidis, Athanasios; Vlachogianni, Thomais; Fiotakis, Konstantinos; Loridas, Spyridon

doi:10.3390/ijerph10093886

Public

Pulmonary Oxidative Stress, Inflammation and Cancer: Respirable Particulate Matter, Fibrous Dusts and Ozone as Major Causes of Lung Carcinogenesis through Reactive Oxygen Species Mechanisms

Published in International Journal of Environmental Research and Public Health • Aug 27, 2013

Authors:

Athanasios Valavanidis

Thomais Vlachogianni

Konstantinos Fiotakis

Abstract

Reactive oxygen or nitrogen species (ROS, RNS) and oxidative stress in the respiratory system increase the production of mediators of pulmonary inflammation and initiate or promote mechanisms of carcinogenesis. The lungs are exposed daily to oxidants generated either endogenously or exogenously (air...

Subject

Oxidative stress

Reactive oxygen species

Particulates

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