Expression of the RND-Type Efflux Pump AdeABC in <i>Acinetobacter baumannii</i> Is Regulated by the AdeRS Two-Component System

Marchand, Isabelle; Damier-Piolle, Laurence; Courvalin, Patrice; Lambert, Thierry

doi:10.1128/aac.48.9.3298-3304.2004

Public

Expression of the RND-Type Efflux Pump AdeABC in Acinetobacter baumannii Is Regulated by the AdeRS Two-Component System

Published in Antimicrobial Agents and Chemotherapy • Aug 24, 2004

Authors:

Isabelle Marchand

Laurence Damier-Piolle

Patrice Courvalin

Abstract

The AdeABC pump of Acinetobacter baumannii BM4454, which confers resistance to various antibiotic classes including aminoglycosides, is composed of the AdeA, AdeB, and AdeC proteins; AdeB is a member of the RND superfamily. The adeA, adeB, and adeC genes are contiguous and adjacent to adeS and adeR,...

Subject

Acinetobacter baumannii

Efflux

Biology

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