Localization of the melanocortin-4 receptor (MC4-R) in neuroendocrine and autonomic control circuits in the brain.

G. Mountjoy, Kathleen; Mortrud, Marty; J. Low, Malcolm; B. Simerly, Richard; D. Cone, Roger

doi:10.1210/mend.8.10.7854347

Public

Localization of the melanocortin-4 receptor (MC4-R) in neuroendocrine and autonomic control circuits in the brain.

Published in Molecular Endocrinology • Oct 1, 1994

Authors:

Kathleen G. Mountjoy

Marty Mortrud

Malcolm J. Low

Abstract

POMC, the precursor of ACTH, MSH, and beta-endorphin peptides, is expressed in the pituitary and in two sites in the brain, in the arcuate nucleus of the hypothalamus and the commissural nucleus of the solitary tract of the brain stem. Little is known regarding the functions of melanocortin (ACTH an...

Subject

Biology

Hypothalamus

Melanocortin

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