Stromal Gene Signatures in Large-B-Cell Lymphomas

Lenz, Georg; W. Wright, George; S. Davé, Sandeep; Xiao, Wenming; Powell, John; Zhao, Hong; Xu, Weihong; K. Tan, Bruce; Goldschmidt, Neta; Iqbal, Javeed; Vose, Julie; Bast, M.; Fu, Kai; Weisenburger, DD; C. Greiner, Timothy; O. Armitage, Jamés; H. Kyle, Alastair; F. May, Lorraine; D. Gascoyne, Randy; M. Connors, Joseph; Trøen, Gunhild; Holte, Harald; Kvaløy, Stein; Dierickx, Daan; Verhoef, G.; Delabie, Jan; B. Smeland, Erlend; Jares, Pedro; Martı́nez, Antonio; López‐Guillermo, Armando; Montserrat, Emili; Campo, Elı́as; M. Braziel, Rita; P. Miller, Thomas; M. Rimsza, Lisa; R. Cook, James; Pohlman, Brad; Sweetenham, John; R. Tubbs, Raymond; I. Fisher, Richard; Hartmann, Elena; Rosenwald, Andreas; Ott, German; Hk, Müller-Hermelink; Wrench, David; Lister, T.; S. Jaffe, Elaine; H. Wilson, Wyndham; C. Chan, Wing; M. Staudt, Louis

doi:10.1056/nejmoa0802885

Public

Stromal Gene Signatures in Large-B-Cell Lymphomas

Published in New England Journal of Medicine • Nov 26, 2008

Authors:

Georg Lenz

George W. Wright

Sandeep S. Davé

Abstract

BACKGROUND: The addition of rituximab to combination chemotherapy with cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP), or R-CHOP, has significantly improved the survival of patients with diffuse large-B-cell lymphoma. Whether gene-expression signatures correlate with survival afte...

Subject

Vincristine

Medicine

Rituximab

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