Confirmation of ALDH2 as a Major Locus of Drinking Behavior and of Its Variants Regulating Multiple Metabolic Phenotypes in a Japanese Population

Takeuchi, Fumihiko; Isono, Masato; Nabika, Toru; Katsuya, Tomohiro; Sugiyama, Takao; Yamaguchi, Shuhei; Kobayashi, Shotai; Ogihara, Toshio; Yamori, Yukio; Fujioka, Akihiro; Kato, Norihiro

doi:10.1253/circj.cj-10-0774

Public

Confirmation of ALDH2 as a Major Locus of Drinking Behavior and of Its Variants Regulating Multiple Metabolic Phenotypes in a Japanese Population

Published in Circulation Journal • Jan 1, 2011

Authors:

Fumihiko Takeuchi

Masato Isono

Toru Nabika

Abstract

BACKGROUND: Normative alcohol use (or drinking behavior) influences the risk of cardiovascular disease in a multi-faceted manner. To identify susceptibility gene variants for drinking behavior, a 2-staged genome-wide association study was performed in a Japanese population. METHODS AND RESULTS: In t...

Subject

ALDH2

Genome-wide association study

Single-nucleotide polymorphism

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!