Comparison of Antiarrhythmic Drug Therapy and Radiofrequency Catheter Ablation in Patients With Paroxysmal Atrial Fibrillation

J. Wilber, David; Pappone, Carlo; Neužil, Petr; de Paola, Angelo; Marchlinski, Frank; Natale, Andrea; Macle, Laurent; G. Daoud, Emile; Calkins, Hugh; Hall, Burr; Y. Reddy, Vivek; Augello, Giuseppe; R. Reynolds, Matthew; Vinekar, Chandan; Y. Liu, Christine; Berry, Scott; A. Berry, Donald; the ThermoCool AF Trial Investigators, for

doi:10.1001/jama.2009.2029

Public

Comparison of Antiarrhythmic Drug Therapy and Radiofrequency Catheter Ablation in Patients With Paroxysmal Atrial Fibrillation

Published in JAMA • Jan 26, 2010

Authors:

David J. Wilber

Carlo Pappone

Petr Neužil

Abstract

CONTEXT: Antiarrhythmic drugs are commonly used for prevention of recurrent atrial fibrillation (AF) despite inconsistent efficacy and frequent adverse effects. Catheter ablation has been proposed as an alternative treatment for paroxysmal AF. OBJECTIVE: To determine the efficacy of catheter ablatio...

Subject

Medicine

Atrial fibrillation

Catheter ablation

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