Age‐related decrease in stimulated glutamate release and vesicular glutamate transporters in APP/PS1 transgenic and wild‐type mice

Minkeviciene, R.; Ihalainen, J.; Malm, T.; Matilainen, O.; Keksa‐Goldsteine, V.; Goldsteins, G.; Iivonen, H.; Leguit, N.; Glennon, J.; Koistinaho, J.; Banerjee, P.; Tanila, H.

doi:10.1111/j.1471-4159.2007.05147.x

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Age‐related decrease in stimulated glutamate release and vesicular glutamate transporters in APP/PS1 transgenic and wild‐type mice

Shared by NobleBlocks on Nov 27, 2007 • 12:00 AM UTC

Authors:

R. Minkeviciene

J. Ihalainen

T. Malm

Abstract

Abstract We assessed baseline and KCl‐stimulated glutamate release by using microdialysis in freely moving young adult (7 months) and middle‐aged (17 months) transgenic mice carrying mutated human amyloid precursor protein and presenilin genes (APdE9 mice) and their wild‐type littermates. In additio...

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