Prophylactic Oophorectomy in Carriers of<i>BRCA1</i>or<i>BRCA2</i>Mutations

R. Rebbeck, Timothy; T. Lynch, Henry; L. Neuhausen, Susan; A. Narod, Steven; van’t Veer, Laura; E. Garber, Judy; Gareth Evans, D.; Isaacs, Claudine; B. Daly, Mary; Matloff, Ellen; I. Olopade, Olufunmilayo; L. Weber, Barbara

doi:10.1056/nejmoa012158

Public

Prophylactic Oophorectomy in Carriers ofBRCA1orBRCA2Mutations

Published in New England Journal of Medicine • May 23, 2002

Authors:

Timothy R. Rebbeck

Henry T. Lynch

Susan L. Neuhausen

Abstract

BACKGROUND: Data concerning the efficacy of bilateral prophylactic oophorectomy for reducing the risk of gynecologic cancer in women with BRCA1 or BRCA2 mutations are limited. We investigated whether this procedure reduces the risk of cancers of the coelomic epithelium and breast in women who carry ...

Subject

Medicine

Oophorectomy

Ovarian cancer

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