Distinct Expression Levels and Patterns of Stem Cell Marker, Aldehyde Dehydrogenase Isoform 1 (ALDH1), in Human Epithelial Cancers

Deng, Shan; Yang, Xiaojun; Lassus, Heini; Liang, Shun; Kaur, Sippy; Ye, Qunrui; Li, Chunsheng; Wang, Liping; F. Roby, Katherine; Oršulić, Sandra; C. Connolly, Denise; Zhang, Youcheng; T. Montone, Kathleen; Bützow, Ralf; Coukos, George; Zhang, Lin

doi:10.1371/journal.pone.0010277

Public

Distinct Expression Levels and Patterns of Stem Cell Marker, Aldehyde Dehydrogenase Isoform 1 (ALDH1), in Human Epithelial Cancers

Published in PLoS ONE • Apr 21, 2010

Authors:

Shan Deng

Xiaojun Yang

Heini Lassus

Abstract

Aldehyde dehydrogenase isoform 1 (ALDH1) has been proved useful for the identification of cancer stem cells. However, our knowledge of the expression and activity of ALDH1 in common epithelial cancers and their corresponding normal tissues is still largely absent. Therefore, we characterized ALDH1 e...

Subject

Cancer stem cell

Biology

Aldehyde dehydrogenase

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