Clinicopathologic Correlations in a Large Alzheimer Disease Center Autopsy Cohort

T. Nelson, Peter; A. Jicha, Gregory; A. Schmitt, Frederick; Liu, Huaichen; G. Davis, Daron; S. Mendiondo, Marta; L. Abner, Erin; R. Markesbery, William

doi:10.1097/nen.0b013e31815c5efb

Public

Clinicopathologic Correlations in a Large Alzheimer Disease Center Autopsy Cohort

Published in Journal of Neuropathology & Experimental Neurology • Dec 1, 2007

Authors:

Peter T. Nelson

Gregory A. Jicha

Frederick A. Schmitt

Abstract

There is uncertainty regarding the association of cognitive decline in Alzheimer disease (AD) with classic histopathologic features- neurofibrillary tangles (NFTs) and "neuritic" amyloid plaques (NPs). This uncertainty fuels doubts about the diagnostic importance of NFTs and NPs and leads to confusi...

Subject

Senile plaques

Medicine

Pathogenesis

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!