The Second Type VI Secretion System of Pseudomonas aeruginosa Strain PAO1 Is Regulated by Quorum Sensing and Fur and Modulates Internalization in Epithelial Cells

G. Sana, Thibault; Hachani, Abderrahman; Bucior, Iwona; Soscia, Chantal; Garvis, Steve; Termine, Elise; N. Engel, Joanne; Filloux, Alain; Bleves, Sophie

doi:10.1074/jbc.m112.376368

Public

The Second Type VI Secretion System of Pseudomonas aeruginosa Strain PAO1 Is Regulated by Quorum Sensing and Fur and Modulates Internalization in Epithelial Cells

Published in Journal of Biological Chemistry • Jun 5, 2012

Authors:

Thibault G. Sana

Abderrahman Hachani

Iwona Bucior

Abstract

The genome of Pseudomonas aeruginosa PAO1 contains three type VI secretion systems (T6SSs) called H1-, H2-, and H3-T6SS. The H1-T6SS secretes three identified toxins that target other bacteria, providing a fitness advantage for P. aeruginosa, and likely contributes to bacterial pathogenesis in chron...

Subject

Type VI secretion system

Pseudomonas aeruginosa

Quorum sensing

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!