Rapid Identification of Intact Whole Bacteria Based on Spectral Patterns using Matrix-assisted Laser Desorption/Ionization with Time-of-flight Mass Spectrometry

D. Holland, Ricky; G. Wilkes, Jon; Rafii, Fatemeh; B. Sutherland, John; Persons, Chance; J. Voorhees, Kent; O. Lay, Jackson

doi:10.1002/(sici)1097-0231(19960731)10:10<1227::aid-rcm659>3.0.co;2-6

Public

Rapid Identification of Intact Whole Bacteria Based on Spectral Patterns using Matrix-assisted Laser Desorption/Ionization with Time-of-flight Mass Spectrometry

Published in Rapid Communications in Mass Spectrometry • Jul 31, 1996

Authors:

Ricky D. Holland

Jon G. Wilkes

Fatemeh Rafii

Abstract

Matrix assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOFMS) was investigated as a method for the rapid identification of whole bacteria, either by comparison with archived reference spectra or by co-analysis with cultures of known bacteria. Bacteria were sampled from c...

Subject

Chemistry

Mass spectrometry

Mass spectrum

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