Genome-wide search for linkage of bipolar affective disorders in a very large pedigree derived from a homogeneous population in Quebec points to a locus of major effect on chromosome 12q23-q24

Morissette, J; Villeneuve, A; Bordeleau, Lise; Rochette, Denis; Laberge, Claude; Gagn�, B.; Laprise, Catherine; Bouchard, G.; Plante, M.; Gobeil, Lise-Andrée; Shink, Éric; Weissenbach, J.; Barden, Nicholas

doi:10.1002/(sici)1096-8628(19991015)88:5<567::aid-ajmg24>3.0.co;2-8

Public

Genome-wide search for linkage of bipolar affective disorders in a very large pedigree derived from a homogeneous population in Quebec points to a locus of major effect on chromosome 12q23-q24

Published in American Journal of Medical Genetics • Oct 15, 1999

Authors:

J Morissette

A Villeneuve

Lise Bordeleau

Abstract

We completed a genome-wide scan for susceptibility loci for bipolar affective disorders in families derived from a rather homogeneous population in the Province of Québec. The genetic homogeneity of this population stems from the migration of founding families into this relatively isolated area of Q...

Subject

Population

Genetics

Proband

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