microRNA 126 Inhibits the Transition of Endothelial Progenitor Cells to Mesenchymal Cells via the PIK3R2-PI3K/Akt Signalling Pathway

Zhang, Junfeng; Zhang, Zongqi; Y. Zhang, David; Zhu, Jianbing; Zhang, Tiantian; Wang, Changqian

doi:10.1371/journal.pone.0083294

Public

microRNA 126 Inhibits the Transition of Endothelial Progenitor Cells to Mesenchymal Cells via the PIK3R2-PI3K/Akt Signalling Pathway

Published in PLoS ONE • Dec 13, 2013

Authors:

Junfeng Zhang

Zongqi Zhang

David Y. Zhang

Abstract

AIMS: Endothelial progenitor cells (EPCs) are capable of proliferating and differentiating into mature endothelial cells, and they have been considered as potential candidates for coronary heart disease therapy. However, the transition of EPCs to mesenchymal cells is not fully understood. This study...

Subject

Mesenchymal stem cell

Gene knockdown

Cell biology

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