Capsular polysaccharides galactoxylomannan and glucuronoxylomannan from Cryptococcus neoformans induce macrophage apoptosis mediated by Fas ligand

N. Villena, Suellen; Olmo Pinheiro, Roberta; S. Pinheiro, Carla; P. Nunes, Marise; Maeda Takiya, Christina; A. DosReis, George; O. Previato, José; Mendonça‐Previato, Lúcia; Geraldo Freire-de-Lima, Célio

doi:10.1111/j.1462-5822.2008.01125.x

Public

Capsular polysaccharides galactoxylomannan and glucuronoxylomannan from Cryptococcus neoformans induce macrophage apoptosis mediated by Fas ligand

Published in Cellular Microbiology • Jan 30, 2008

Authors:

Suellen N. Villena

Roberta Olmo Pinheiro

Carla S. Pinheiro

Abstract

The effects of capsular polysaccharides, galactoxylomannan (GalXM) and glucuronoxylomannan (GXM), from acapsular (GXM negative) and encapsulate strains of Cryptococcus neoformans were investigated in RAW 264.7 and peritoneal macrophages. Here, we demonstrate that GalXM and GXM induced different cyto...

Subject

Cryptococcus neoformans

Biology

Fas ligand

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