Intense Superoxide Dismutase-1 Immunoreactivity in Intracytoplasmic Hyaline Inclusions of Familial Amyotrophic Lateral Sclerosis with Posterior Column Involvement

Shibata, Noriyuki; Hirano, Asao; Kobayashi, Makio; Siddique, Teepu; Deng, Han‐Xiang; Hung, Wu-Yen; Kato, Takeo; Asayama, Kohtaro

doi:10.1097/00005072-199604000-00011

Public

Intense Superoxide Dismutase-1 Immunoreactivity in Intracytoplasmic Hyaline Inclusions of Familial Amyotrophic Lateral Sclerosis with Posterior Column Involvement

Published in Journal of Neuropathology & Experimental Neurology • Apr 1, 1996

Authors:

Noriyuki Shibata

Asao Hirano

Makio Kobayashi

Abstract

This report concerns retrospective immunohistochemical and immunoelectron microscopic studies on superoxide dismutase-1 (SOD1) in intracytoplasmic hyaline inclusions (IHIs) of the anterior horn cells of three patients with familial amyotrophic lateral sclerosis (ALS) with posterior column involvemen...

Subject

SOD1

Neurofilament

Amyotrophic lateral sclerosis

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