Transplantation of in vitro‐expanded fetal neural progenitor cells results in neurogenesis and functional recovery after spinal cord contusion injury in adult rats

Ogawa, Y.; Sawamoto, Kazunobu; Miyata, Takaki; Miyao, Sachiyo; Watanabe, Masahiko; Nakamura, Masaya; Bregman, B.S.; Koike, Masato; Uchiyama, Yasuo; Toyama, Y.; Okano, Hideyuki

doi:10.1002/jnr.10341

Public

Transplantation of in vitro‐expanded fetal neural progenitor cells results in neurogenesis and functional recovery after spinal cord contusion injury in adult rats

Published in Journal of Neuroscience Research • Aug 27, 2002

Authors:

Y. Ogawa

Kazunobu Sawamoto

Takaki Miyata

Abstract

Neural progenitor cells, including neural stem cells, are a potential expandable source of graft material for transplantation aimed at repairing the damaged CNS. Here we present the first evidence that in vitro-expanded fetus-derived neurosphere cells were able to generate neurons in vivo and improv...

Subject

Neurosphere

Spinal cord injury

Transplantation

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