Essential Requirement of BMPs-2/4 for Both Osteoblast and Osteoclast Formation in Murine Bone Marrow Cultures from Adult Mice: Antagonism by Noggin

Abe, Etsuko; Yamamoto, Matsuo; Taguchi, Yasuto; Lecka-Czernik, Beata; A. O'Brien, Charles; N. Economides, Aris; Stahl, Neil; L. Jilka, Robert; C. Manolagas, Stavros

doi:10.1359/jbmr.2000.15.4.663

Public

Essential Requirement of BMPs-2/4 for Both Osteoblast and Osteoclast Formation in Murine Bone Marrow Cultures from Adult Mice: Antagonism by Noggin

Shared by NobleBlocks on Apr 1, 2000 • 12:00 AM UTC

Authors:

Etsuko Abe

Matsuo Yamamoto

Yasuto Taguchi

Abstract

Abstract Bone morphogenetic proteins (BMPs) have been heretofore implicated in the induction of osteoblast differentiation from uncommitted progenitors during embryonic skeletogenesis and fracture healing. We have tested the hypothesis that BMPs are also involved in the osteoblastogenesis that takes...

Discussions