Human Dental Pulp Stem Cells Improve Left Ventricular Function, Induce Angiogenesis, and Reduce Infarct Size in Rats with Acute Myocardial Infarction

Gandía, Carolina; Armiñán, Ana; Manuel García‐Verdugo, José; Lledó, Elisa; Ruı́z, Amparo; Dolores Miñana, María; Sánchez-Torrijos, Jorge; Payá, Rafael; Mirabet, Vicente; Carbonell‐Uberos, Francisco; Llop, Mauro; Montero, José; Sepúlveda, Pilar

doi:10.1634/stemcells.2007-0484

Public

Human Dental Pulp Stem Cells Improve Left Ventricular Function, Induce Angiogenesis, and Reduce Infarct Size in Rats with Acute Myocardial Infarction

Published in Stem Cells • Dec 13, 2007

Authors:

Carolina Gandía

Ana Armiñán

José Manuel García‐Verdugo

Abstract

Human dental pulp contains precursor cells termed dental pulp stem cells (DPSC) that show self-renewal and multilineage differentiation and also secrete multiple proangiogenic and antiapoptotic factors. To examine whether these cells could have therapeutic potential in the repair of myocardial infar...

Subject

Myocardial infarction

Biology

Angiogenesis

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