Novel heterocyclic analogs of the new potent class of calcium entry blockers: 1-[[4-(aminoalkoxy)phenyl]sulfonyl]indolizines

Gubin, J.; DE VOGELAER, H.; INION, H.; HOUBEN, CHRISTIAN; Lucchetti, J.; Mahaux, Jean; ROSSEELS, G.; A. Peiren, Maurits; Clinet, M.

doi:10.1021/jm00062a015

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Novel heterocyclic analogs of the new potent class of calcium entry blockers: 1-[[4-(aminoalkoxy)phenyl]sulfonyl]indolizines

Published in Journal of Medicinal Chemistry • May 1, 1993

Authors:

J. Gubin

H. DE VOGELAER

H. INION

Abstract

Several heterocyclic analogues of the potent 1-[[4-(aminoalkoxy)phenyl]sulfonyl]indolizines were synthesized and evaluated for their antagonistic calcium activities in comparison with the 1-sulfonylindolizine SR 33557 and the usual calcium antagonist references verapamil, cis-(+)-diltiazem, and nife...

Subject

Citation

Sulfonyl

Class (philosophy)

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