Immune Activation by Life-Shortening Wolbachia and Reduced Filarial Competence in Mosquitoes

Wolbachia strain wMelPop reduces the longevity of its Drosophila melanogaster host and, when introduced into the mosquito Aedes aegypti, halves its life span. We show that wMelPop induces up-regulation of the mosquito's innate immune system and that its presence inhibits the development of filarial ... View More