Adipose-derived mesenchymal stem cell transplantation promotes adult neurogenesis in the brains of Alzheimer's disease mice

Yan, Yufang; Ma, Tuo; Gong, Kai; Ao, Qiang; Zhang, Xiufang; Gong, Yandao

doi:10.4103/1673-5374.131596

Public

Adipose-derived mesenchymal stem cell transplantation promotes adult neurogenesis in the brains of Alzheimer's disease mice

Published in Neural Regeneration Research • Apr 15, 2014

Authors:

Yufang Yan

Tuo Ma

Kai Gong

Abstract

In the present study, we transplanted adipose-derived mesenchymal stem cells into the hippocampi of APP/PS1 transgenic Alzheimer's disease model mice. Immunofluorescence staining revealed that the number of newly generated (BrdU(+)) cells in the subgranular zone of the dentate gyrus in the hippocamp...

Subject

Subgranular zone

Neurogenesis

Mesenchymal stem cell

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!