Randomized Trial of High Loading Dose of Clopidogrel for Reduction of Periprocedural Myocardial Infarction in Patients Undergoing Coronary Intervention

Patti, Giuseppe; Colonna, Giuseppe; Pasceri, Vincenzo; Lassandro Pepe, Leonardo; Montinaro, Antonio; Di Sciascio, Germano

doi:10.1161/01.cir.0000161383.06692.d4

Public

Randomized Trial of High Loading Dose of Clopidogrel for Reduction of Periprocedural Myocardial Infarction in Patients Undergoing Coronary Intervention

Published in Circulation • Mar 6, 2005

Authors:

Giuseppe Patti

Giuseppe Colonna

Vincenzo Pasceri

Abstract

BACKGROUND: Aggressive platelet inhibition is crucial to reduce myocardial injury and early cardiac events after coronary intervention. Although observational data have suggested that pretreatment with a high loading dose of clopidogrel may be more effective than a conventional dose, this hypothesis...

Subject

Medicine

Clopidogrel

Loading dose

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