Soluble Endoglin and Other Circulating Antiangiogenic Factors in Preeclampsia

J. Levine, Richard; Sing Lam, Chun; Qian, Cong; F. Yu, Kai; E. Maynard, Sharon; Sachs, Benjamin; M. Sibai, Baha; H. Epstein, Franklin; Romero, Roberto; Thadhani, Ravi; Ananth Karumanchi, S.

doi:10.1056/nejmoa055352

Public

Soluble Endoglin and Other Circulating Antiangiogenic Factors in Preeclampsia

Published in New England Journal of Medicine • Sep 6, 2006

Authors:

Richard J. Levine

Chun Sing Lam

Cong Qian

Abstract

BACKGROUND: Alterations in circulating soluble fms-like tyrosine kinase 1 (sFlt1), an antiangiogenic protein, and placental growth factor (PlGF), a proangiogenic protein, appear to be involved in the pathogenesis of preeclampsia. Since soluble endoglin, another antiangiogenic protein, acts together ...

Subject

Preeclampsia

Medicine

Liter

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