Rituximab and dexamethasone vs dexamethasone monotherapy in newly diagnosed patients with primary immune thrombocytopenia.

Gudbrandsdottir, Sif; Sverre Birgens, Henrik; Frederiksen, Henrik; Anker Jensen, Bjarne; Krogh Jensen, Morten; Kjeldsen, Lars; Wirenfeldt Klausen, Tobias; Larsen, Herdis; Torben Mourits-Andersen, Hans; Henrik Nielsen, Claus; Juul Nielsen, Ove; Plesner, Torben; Pulczynski, Stanislaw; Helleberg Rasmussen, Inge; Rønnov-Jessen, Dorthe; Carl Hasselbalch, Hans

doi:10.1182/blood-2012-09-455691

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Rituximab and dexamethasone vs dexamethasone monotherapy in newly diagnosed patients with primary immune thrombocytopenia.

Shared by NobleBlocks on Mar 14, 2013 • 12:00 AM UTC

Authors:

Sif Gudbrandsdottir

Henrik Sverre Birgens

Henrik Frederiksen

Abstract

In this study, we report the results from the largest cohort to date of newly diagnosed adult immune thrombocytopenia patients randomized to treatment with dexamethasone alone or in combination with rituximab. Eligible were patients with platelet counts ≤25×10(9)/L or ≤50×10(9)/L with bleeding sympt...

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