Efficacy of Intravenous Liposomal Amphotericin B (AmBisome) against Coccidioidal Meningitis in Rabbits

V. Clemons, Karl; A. Sobel, Raymond; L. Williams, Paul; Pappagianis, Demosthenes; A. Stevens, David

doi:10.1128/aac.46.8.2420-2426.2002

Public

Efficacy of Intravenous Liposomal Amphotericin B (AmBisome) against Coccidioidal Meningitis in Rabbits

Published in Antimicrobial Agents and Chemotherapy • Jul 28, 2002

Authors:

Karl V. Clemons

Raymond A. Sobel

Paul L. Williams

Abstract

The efficacy of intravenously administered liposomal amphotericin B (AmBisome [AmBi]) for the treatment of experimental coccidioidal meningitis was compared with those of oral fluconazole (FLC) and intravenously administered conventional amphotericin B (AMB). Male New Zealand White rabbits were infe...

Subject

Amphotericin B

Medicine

Cerebrospinal fluid

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