Cell Entry of Hepatitis C Virus Requires a Set of Co-receptors That Include the CD81 Tetraspanin and the SR-B1 Scavenger Receptor

Bartosch, Birke; Vitelli, Alessandra; Granier, Christelle; Goujon, Caroline; Dubuisson, Jean; Pascale, Simona; Scarselli, Elisa; Cortese, Riccardo; Nicosia, Alfredo; Cosset, François‐Loïc

doi:10.1074/jbc.m305289200

Public

Cell Entry of Hepatitis C Virus Requires a Set of Co-receptors That Include the CD81 Tetraspanin and the SR-B1 Scavenger Receptor

Published in Journal of Biological Chemistry • Oct 1, 2003

Authors:

Birke Bartosch

Alessandra Vitelli

Christelle Granier

Abstract

Several cell surface molecules have been proposed as receptor candidates, mediating cell entry of hepatitis C virus (HCV) on the basis of their physical association with virions or with soluble HCV E2 glycoproteins. However, due to the lack of infectious HCV particles, evidence that these receptor c...

Subject

CD81

Tetraspanin

Scavenger receptor

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