Identification of Restricted Subsets of Mature microRNA Abnormally Expressed in Inactive Colonic Mucosa of Patients with Inflammatory Bowel Disease

Fasseu, Magali; Tréton, Xavier; Guichard, Cécile; Pédruzzi, Eric; Cazals‐Hatem, Dominique; Richard, Christophe; Aparicio, Thomas; Daniel, Fanny; Soulé, Jean–Claude; Moreau, Richard; Bouhnik, Yoram; Laburthe, Marc; Groyer, André; Ogier‐Denis, Éric

doi:10.1371/journal.pone.0013160

Public

Identification of Restricted Subsets of Mature microRNA Abnormally Expressed in Inactive Colonic Mucosa of Patients with Inflammatory Bowel Disease

Published in PLoS ONE • Oct 5, 2010

Authors:

Magali Fasseu

Xavier Tréton

Cécile Guichard

Abstract

BACKGROUND: Ulcerative Colitis (UC) and Crohn's Disease (CD) are two chronic Inflammatory Bowel Diseases (IBD) affecting the intestinal mucosa. Current understanding of IBD pathogenesis points out the interplay of genetic events and environmental cues in the dysregulated immune response. We hypothes...

Subject

microRNA

Pathogenesis

Inflammatory bowel disease

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