Advanced lipid peroxidation end products in oxidative damage to proteins. Potential role in diseases and therapeutic prospects for the inhibitors

Nègre‐Salvayre, Anne; Coatrieux, Christelle; Ingueneau, Cécile; Salvayre, Robert

doi:10.1038/sj.bjp.0707395

Public

Advanced lipid peroxidation end products in oxidative damage to proteins. Potential role in diseases and therapeutic prospects for the inhibitors

Published in British Journal of Pharmacology • Jul 23, 2007

Authors:

Anne Nègre‐Salvayre

Christelle Coatrieux

Cécile Ingueneau

Abstract

Reactive carbonyl compounds (RCCs) formed during lipid peroxidation and sugar glycoxidation, namely Advanced lipid peroxidation end products (ALEs) and Advanced Glycation end products (AGEs), accumulate with ageing and oxidative stress-related diseases, such as atherosclerosis, diabetes or neurodege...

Subject

Lipid peroxidation

Oxidative stress

Glycation

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