Human immunodeficiency virus infection of human brain capillary endothelial cells occurs via a CD4/galactosylceramide-independent mechanism.

V. Moses, Ashlee; E. Bloom, Floyd; David Pauza, C.; A. Nelson, Jay

doi:10.1073/pnas.90.22.10474

Public

Human immunodeficiency virus infection of human brain capillary endothelial cells occurs via a CD4/galactosylceramide-independent mechanism.

Published in Proceedings of the National Academy of Sciences • Nov 15, 1993

Authors:

Ashlee V. Moses

Floyd E. Bloom

C. David Pauza

Abstract

Neuropathologic studies of AIDS patients have shown that brain capillary endothelial cells are a cellular target for human immunodeficiency virus (HIV) in vivo. We have established in vitro cultures of primary human brain capillary endothelial (HBCE) cells. Using this model system, we have shown a s...

Subject

Neuropathology

Central nervous system

Human immunodeficiency virus (HIV)

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