Characterization of the Cholesterol Recognition Amino Acid Consensus Sequence of the Peripheral-Type Benzodiazepine Receptor

Jamin, Nadège; Neumann, Jean‐Michel; A. Ostuni, Mariano; Kim Ngoc Vu, Thi; Yao, Zhixing; Murail, Samuel; Robert, Jean‐Claude; Giatzakis, Christoforos; Papadopoulos, Vassilios; Lacapère, J

doi:10.1210/me.2004-0308

Public

Characterization of the Cholesterol Recognition Amino Acid Consensus Sequence of the Peripheral-Type Benzodiazepine Receptor

Published in Molecular Endocrinology • Nov 5, 2004

Authors:

Nadège Jamin

Jean‐Michel Neumann

Mariano A. Ostuni

Abstract

We previously defined a cholesterol recognition/interaction amino acid consensus sequence [CRAC: L/V-X (1-5)-Y-X (1-5)-R/K] in the carboxyl terminus of the peripheral-type benzodiazepine receptor (PBR), a high-affinity drug and cholesterol-binding protein present in the outer mitochondrial membrane ...

Subject

Biology

Consensus sequence

Benzodiazepine

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