Characterization of the Murine Antigenic Determinant, Designated L3T4a, Recognized by Monoclonal Antibody GK 1.5: Expression of L3T4a by Functional T Cell Clones Appears to Correlate Primarily with Class II MHC Antigen‐Reactivity

P. Dialynas, Deno; B Wilde, D; Marrack, Philippa; Pierres, A; A. Wall, Katherine; L. Havran, Wendy; R. Otten, Gillis; R. Loken, Michael; Pierres, Michel; W. Kappler, John; W. Fitch, Frank

doi:10.1111/j.1600-065x.1983.tb01083.x

Public

Characterization of the Murine Antigenic Determinant, Designated L3T4a, Recognized by Monoclonal Antibody GK 1.5: Expression of L3T4a by Functional T Cell Clones Appears to Correlate Primarily with Class II MHC Antigen‐Reactivity

Published in Immunological Reviews • Sep 1, 1983

Authors:

Deno P. Dialynas

D B Wilde

Philippa Marrack

Abstract

We describe here the properties of mAb GK1.5, which recognizes a cell surface molecule designated L3T4; the determinant on L3T4 recognized by mAb GK1.5 is designated L3T4a. We present evidence here that: i) the expression of L3T4a by murine T cell clones correlates primarily with class II MHC antige...

Subject

Antigen

Biology

Major histocompatibility complex

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