Tenofovir-Based Preexposure Prophylaxis for HIV Infection among African Women

Marrazzo, Jeanne; Ramjee, Gita; A. Richardson, Barbra; Gomez, Kailazarid; Mgodi, Nyaradzo; Nair, Gonasagrie; Palanee, Thesla; Nakabiito, Clemensia; van der Straten, Ariane; Noguchi, Lisa; W. Hendrix, Craig; Y. Dai, James; Ganesh, Shayhana; Mkhize, Baningi; Taljaard, Marthinette; M. Parikh, Urvi; Piper, Jeanna; Mâsse, Benoı̂t; Grossman, Cynthia; F. Rooney, James; L. Schwartz, Jill; Watts, Heather; A. Marzinke, Mark; L. Hillier, Sharon; McGowan, Ian; M. Chirenje, Zvavahera

doi:10.1056/nejmoa1402269

Public

Tenofovir-Based Preexposure Prophylaxis for HIV Infection among African Women

Published in New England Journal of Medicine • Feb 4, 2015

Authors:

Jeanne Marrazzo

Gita Ramjee

Barbra A. Richardson

Abstract

BACKGROUND: Reproductive-age women need effective interventions to prevent the acquisition of human immunodeficiency virus type 1 (HIV-1) infection. METHODS: We conducted a randomized, placebo-controlled trial to assess daily treatment with oral tenofovir disoproxil fumarate (TDF), oral tenofovir-em...

Subject

Medicine

Hazard ratio

Pre-exposure prophylaxis

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