Suspended cells from trabecular bone by collagenase digestion become virtually identical to mesenchymal stem cells obtained from marrow aspirates

Sakaguchi, Yusuke; Sekiya, Ichiro; Yagishita, Kazuyoshi; Ichinose, Shizuko; Shinomiya, Kenichi; Muneta, Takeshi

doi:10.1182/blood-2003-12-4452

Public

Suspended cells from trabecular bone by collagenase digestion become virtually identical to mesenchymal stem cells obtained from marrow aspirates

Published in Blood • Jul 8, 2004

Authors:

Yusuke Sakaguchi

Ichiro Sekiya

Kazuyoshi Yagishita

Abstract

Several reports describe that the explant culture of the trabecular bone after collagenase treatment produces mesenchymal stem cells (MSCs). However, the suspended cells had not been intensively examined concerning MSCs. We hypothesized that the cells would acquire the properties of MSCs during thei...

Subject

Mesenchymal stem cell

Bone marrow

Collagenase

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