Cigarette smoking is associated with dose-related and potentially reversible impairment of endothelium-dependent dilation in healthy young adults.

S. Celermajer, David; E. Sørensen, Keld; Georgakopoulos, Dimitri; Bull, Catherine; Thomas, O; Robinson, J.; Deanfield, John

doi:10.1161/01.cir.88.5.2149

Public

Cigarette smoking is associated with dose-related and potentially reversible impairment of endothelium-dependent dilation in healthy young adults.

Published in Circulation • Nov 1, 1993

Authors:

David S. Celermajer

Keld E. Sørensen

Dimitri Georgakopoulos

Abstract

BACKGROUND: Cigarette smoking is the most important modifiable risk factor for atherosclerosis. Endothelial dysfunction is an early event in atherogenesis, and we hypothesized that smoking might be associated with endothelial damage in the systemic arteries of otherwise healthy young adults. METHODS...

Subject

Medicine

Brachial artery

Reactive hyperemia

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